First of all, the GCS brand (OpenPilot or LibrePilot) and version number needs to match the firmware in the CC3D. Second, to run the current version of LP, you may need to update your CC3D bootloader. Third, when you install OpenPilot or LibrePilot, it automatically installs the needed Windows drivers and you shouldn't need to install other drivers. If you installed or removed drivers after installing the GCS, you may want to reinstall the GCS to fix the drivers.
If you bought an RTF quad that has OP on it, then it is probably a good idea to download the matching version of OP, and install and run it. That gets you in the air and flying so you can at least test it to make sure it works before diving into learning how to set it up from scratch like you would if you started over with LP.
If you are building your own quad you probably want to start with LP because OP is a dead project.