ESC calibration doesn't affect input. Red input means something is wrong with the RC input configuration. I recall that a correctly configured RC input is orange if the RC receiver is not powered.
I suggest you re-run the setup wizard, assuming that you are using PWM RC. This is when you use a cable/wire for each function, so you will have a cable with 3 wires, and about 4 other cables with 1 wire each, going from FC to RC receiver.
Also be careful to read and follow instructions, for instance, the RC receiver only gets power when a flight battery is plugged into the ESC. Also, the ESC must have a built in BEC (battery eliminator circuit) to convert the 12V flight battery power to 5 volts for the RC receiver and the FC. OPTO ESCs generally don't have BECs, but most other, common ESCs do have BECs built in.