Thanks for your reply.
I did reverse motor 1 in BLH, it is set back to normal now, wires changed instead. No change in results in the wizard setup nor manual.
I unticked the Programming by Tx box (even though the pop up says that disables throttle calibration mode, try anything at this point) for each ESC and re-verified for the third time all BLH settings are correct and the same for each controller. Neither manual cal nor wizard cal worked.
I re-ticked the boxes, and when re-connecting ESCs to FC noticed motors 1&4 gave me a beep when re-connected, motors 2&3 did not, as was the case in previous tries. Swapped connectors around, 1&4 gave me a beep where ever connected, 2&3 did not. Hmmmmm.
Opened LP, attempted manual motor neutral setup, motors 1,2(!) and 4 spun up, 3 did not, set neutral for all four at 1025 (Sunnysky 2216-9 1100 BTW).
Disconnected flight battery and pulled USB connecting FC, let everything sit for two minutes, reconnected, tested outputs, all 4 motors spun up! What the? Nothing I dislike more then solving (?) a problem and not knowing what solved it. Motors seem to have stopped twitching too.
Guess I'll go ahead and finish up and try a very cautious test flight.